Publications

Rinaldi V*, Donnard D*, Gellatly K, Rasmussen M, Kucukural A, Yukselen O, Garber M, Sharma U, and Rando O. An atlas of cell types in the mammalian epididymis and vas deferens.  eLife 2020;9:e55474 July 2020.

Sharma U. Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic Information. Front. Cell Dev. Biol., 09 October 2019

Sharma U, Sun F, Conine C, Reichholf B, Kukreja S, Herzog VA, Ameres SL, and Rando OJ. Small RNAs are trafficked from the epididymis to developing mammalian sperm. Developmental Cell 46, 481–494 (2018)

Related news articles:

Dads Pass On More Than Genetics in Their Sperm
https://www.smithsonianmag.com/science-nature/dads-pass-more-genetics-their-sperm-180969760/

Changes to sperm’s small RNA in the epididymis may help ensure mouse embryos implant.

 https://www.sciencedaily.com/releases/2018/07/180726162746.htm

Changes to small RNA in sperm may help fertilization

https://phys.org/news/2018-07-small-rna-sperm-fertilization.html

Ichikawa Y*, Connelly CF*, Appleboim A*, Jacobi H, Abshiru NA, Chou HJ, ChenY, Sharma U,  Zheng Z, Thomas PM, Bajaj V, Kelleher NL, Friedman N, Bolon DN, Rando OJ † and Kaufman PD † A synthetic biology approach to probing nucleosome symmetry, Elife. 2017 10.7554/eLife.28836

Sharma U and Rando OJ. Metabolic inputs into the epigenome, Cell Metabolism 25(3):544-558 (2017)

Sharma U*, Conine CC*, Shea JM, Boskovic A, Derr AG, Bing XY, Belleannee C, Kucukural A, Serra RW, Sun F, Carone BR, Ricci EP, Li XZ, Fauquier L, Moore MJ, Sullivan R, Mello CC, Garber M, and Rando OJ; Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals Science. 2016 Jan 22; 351(6271): 391–396.

Related news articles:

Are you inheriting more than genes from your father?

https://www.sciencemag.org/news/2015/12/are-you-inheriting-more-genes-your-father

A father’s diet affects the RNA of his sperm, mouse study shows

https://www.eurekalert.org/pub_releases/2015-12/aaft-afd122315.php

https://www.nytimes.com/2018/12/10/health/mind-epigenetics-genes.html?action=click&module=Well&pgtype=Homepage&section=Health

Sharma U and Rando OJ; Father-Son Chats: Inheriting Stress through Sperm RNA. Cell Metabolism 19: 894-895 (2014)

Sharma U, Stefanova D, and Holmes SG; Histone variant H2A.Z functions in sister chromatid cohesion in Saccharomyces cerevisiae. 2012 Cell. Biol. 33: 3473-3481 (2012)

Martins-Taylor K*, Sharma U*, Tania Rozario, and Holmes SG. H2A.Z (Htz1) controls the cell-cycle dependent establishment of transcriptional silencing at Saccharomyces cerevisiae Genetics 187:89-104 (2011)

*Authors contributed equally to the manuscript

Please follow this link to find the lab’s publications in the National Library of Medicine’s PubMed database.